Apply 2-3 drops to clean, dry skin on the face and neck in the morning or evening. To maintain optimal efficacy, avoid layering with products containing strong acids (such as pure Vitamin C suspensions, AHAs, or BHAs), which can temporarily destabilize the enzyme. EUK-134 can be mixed with oils or moisturizers. A slight warming sensation upon application is normal. Always use a broad-spectrum sunscreen during the day as part of a complete protective routine.